Welcome to O2H
 
 
Welcome to O2H
 
Heptares Therapeutics extends Multi-FTE collaboration with O2h
 
MRCT and O2h announce medicinal chemistry collaboraion. 
 
O2h at BIO2010 
Chicago, USA, 3-6May 2010 
 
O2h exhibiting at ERBI conference 2010 
Cambridge, UK, 2-3 June 2010 
 
CEO Sunil Shah speaking at SCI Drug Discovery Outsourcing Conference 2010 
London, UK, 9 June 2010 
 
O2h attending BIONJ 2010 
New Jersey, USA, 14-15 June 2010 
 
O2h attending  MassBio Signature event
Boston, USA, October 2010 
 
O2h attending ChemPharma Outsourcing 2010 
New Jersey, USA, 14-16 September 2010 
 
O2h attending BIO Europe 
Munich, Germany, 15-17 November 2010
 
 
New User Register
Computational Chemistry
The computational chemistry team uses sophisticated softwares and techniques to assist Hit-to-lead discovery. O2h has in house computational design capability led by internationally qualified multi-skilled organic, medicinal and computational chemist. O2h have access to the Accelrys suite of design tools to assist hit to lead discovery. The services O2h offers in the computational chemistry area are:
 
Molecular modelling
 
Virtual screening
 
•Target identification
•In-silico drug likeness
•Screening commercial databases to identify focused lead/hit compounds
•Docking
•Prioritise hits for in-vitro studies
 
Drug Designing
 
•Computational support for hit generation and lead optimisation
•Development of pharmacophore models for different target molecules vis-a-vis therapeutic areas
•Universal/focused or specific model
 
Other Services
 
•Designing target focused libraries
•Target modeling
•Molecular dynamic simulations
•Developing highly predictive 3D-QSAR models based on target and therapeutic areas
 
 
Oxygen Healthcare Ltd   23, Cambridge Science park, CB4 0EY , UK   Tel : +44 (0) 1223 437014   info@o2h.com
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